HGH - Growth Factors Growth factors are small proteins produced within the human body that regulate cell growth, cell specialization as well as control metabolic processes. Growth factors enable cells in the immune, nervous and hormonal systems to coordinate their growth and cell functioning plus support cell regeneration. We now know that normal cell growth is controlled by feedback between growth stimulators and growth inhibitors: Growth factors:
- regulate cell growth, division and specialization.
- coordinate immune, nervous and hormonal systems.
- enhance cell communication.
- compete with viruses for expression of the same genetic sites.
Growth factors have significant effects on DNA, RNA, protein synthesis, amino acid uptake, cell migration, cell regeneration, wound repair, collagen repair and cell division. It has been determined that growth factors in the body affect the individual cells by binding to growth-factor-specific receptors on the cell's surface. Receptor binding initiates a sequence of events inside the cell, leading to the cell nucleus where the required action takes
place through its effects on DNA synthesis. The signal from a growth factor affects the cell cycle through positive and negative feedback processes, and may be involved in controlling various cell functions.
Growth factors are well known for their different regulatory roles in the body. Regulatory function differs depending on the condition and type of cell, the presence of different hormones and proteins, and any additional stress factors that may affect tissue integrity. The following descriptions of growth factors are based on known mechanisms of action and their general regulatory roles in the body. As a hormone, human growth hormone (hGH) affects specific target tissues in its role as a chemical messenger. Human growth hormone works with insulin-like growth factor (IGF1) to affect the uptake of nutrients into the cell. |